Prediction of Threats to Multiple Pregnancy Interruption Depending On the Cause of Its Occurrence

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چکیده

The article shows the main ultrasound signs of abortion threat, depending on its causes. The peculiarities of distributing the gene polymorphisms of IL-8 (-781 C/T), MTHFR С677T, Fll G20210А, FV (Leiden) G1691A and PAI-1675 5G/4G were studied and their role at women with a multiple pregnancy miscarriage. The prognostic role of identified genetic predictors in the development of miscarriage is evaluated. In analyzing the frequency of alleles and genotypes indicated risk of reproductive losses, the most significant genetic markers are discovered and the interaction on polymorphisms of studied genes is determined. Careful monitoring the patients with multiple pregnancy in the antenatal period, prevention of the complications of multiple pregnancy, monitoring from the early terms of gestation make it possible to carry out a differentiated approach to womenaging pregnancy and delivery, thus helping decrease perinatal morbidity and mortality.

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تاریخ انتشار 2016